Skin Care Solution—— Multi-recombinant functional raw materials, opening a new era of three-dimensional anti-aging(2-1)

Aging is an inevitable process in life and dominates the boundaries of skin youth. "The most unretainable thing in the world is the beauty of the face, the beauty of the mirror, the beauty of the flowers and the beauty of the trees." As time goes by, the proliferation and differentiation ability of cells gradually declines, and their functions also decline. At the same time, external invasions such as ultraviolet radiation and environmental pollution, and multiple factors such as mitochondrial damage, inflammatory response, and increased ROS lead to a decrease in cell repair ability, which also accelerates skin aging. Affected by age and environmental factors, all levels of the skin are aging. This irreversible damage seriously affects the overall structure and function of the skin, accelerating the aging process of the human body.

(Figure 1) Factors that affect skin problems 

Aging is a multi-layered, multi-dimensional process that extends from the epidermis to the dermis. 

Epidermis  

The epidermis is the first line of defense of the human body and plays a role of barrier protection. A complete barrier function is the underlying logic of anti-aging, and its structure is closely related to epidermal lipids, various proteins and other substances. Epidermal aging is mainly manifested by increased penetration of foreign substances, increased transepidermal water loss, and loss of nutrients, which leads to dry, itchy and sensitive skin, causing various skin problems.

(Figure 2) Structure of the stratum corneum 

Basement membrane  

The basement membrane is located at the junction of the epidermis and the papillary dermis. It is a connecting and transitional structure between the two, which is conducive to the connection between the epidermis and the epidermis, and promotes information transmission and material exchange between the epidermis and the epidermis. The basement membrane is a structure rich in growth factors and extracellular matrix proteins. Its main components include type IV collagen, type VII collagen, type XVII collagen, integrin, etc. The aging basement membrane will undergo morphological changes. The wavy mosaic structure gradually tends to be flat, thin, and even broken. A variety of key proteins are reduced, resulting in sagging skin and wrinkles. 

(Figure 3) Basement membrane structure 

Dermis

The dermis is mainly composed of collagen fibers and elastic fibers, of which collagen accounts for 80%. Collagen fiber bundles provide skin toughness and tensile strength, and the elastic fiber network gives the skin elasticity. The thickness of the dermis tissue is closely related to the number of fibers, which determines the firmness and fullness of the skin. The aging of the dermis is mainly manifested by the reduction of collagen, the degradation and disintegration of the collagen fiber network, which leads to sagging skin, decreased elasticity, and the formation of deep wrinkles.

(Figure 4) Skin structure diagram