Product Category
RSCare REFI Recombinant Fibronectin
Category：
keywords：
cosmetics ingredients I aesthetics I medical dressing I repair skin barrier I anti-aging I hair follicle regeneration
Product description
Description
This product series is a recombinant fibronectin obtained by screening the core functional region fragments, using microbial fermentation, separation and purification. The M.W is 40 kDa, the amino acid sequence is 100% homologous to humans, and has good skin affinity and biocompatibility. It activates macrophages to polarize to the anti-inflammatory M2 type, enhances phagocytic ability, and clears internal damage; activates internal repair power, promotes cell proliferation, migration, and adhesion, and repairs the skin from the inside out; inhibits melanin formation through multiple pathways, and reduces melanin deposition after skin damage. It has good skin damage repair and whitening effects.
Mechanism of efficacy
Fibronectin participates in the entire process of damage repair, promotes cell migration, adhesion, proliferation, tissue repair and other processes, and acts as a growth factor.
Skin damage repair is a complex dynamic regulatory process, which mainly includes the inflammatory phase, proliferation phase, and remodeling phase. These phases overlap in time and involve a series of orderly interactions among cells, cytokines, and extracellular matrix.
● Inflammatory phase
Activate immune cells to remove necrotic tissue and bacteria
● Proliferation phase
Angiogenesis, granulation tissue formation and re-epithelialization
● Remodeling phase
Collagen deposition, reconstruction of the dermis; epidermis restores barrier function
Parameters
| Name | RSCare REFI 500L |
| INCI | Fibronectin, sodium alginate, p-hydroxyacetophenone, 1,2-hexanediol, glycerin, water |
| Apperance | Liquid |
| Active ingredient content | 500 ppm |
| M.W | 40 k Da |
| Recommended dosage | 1-10 % |
| Storage | Store at 2-8℃ in a sealed container away from light |
| Storage | should not be used with strong acids, strong bases, hormones, alcohol and other protein inactivators |
Efficacy
● Enhance macrophage phagocytic activity and clear internal damage;
● Activate internal repair power and repair skin from the inside out;
● Multi-pathway suppression of melanin and reduction of melanin deposition after damage.
Data presentation
● Repair the dermis
Promote cell-collagen adhesion
Positive control: 200ppm bovine type I collagen, 1mg/mL gelatin
FAQ
Q: What is recombinant fibronectin?
A: Recombinant fibronectin is a protein that is produced through recombinant expression in cells. It is a glycoprotein that is part of the extracellular matrix (ECM) and plays a key role in cell adhesion, migration, and growth.
Q: What are the purity detection methods?
A: Usually, we use HPLC and SDS-PAGE to jointly verify the purity of RSCare ALP, indicating that it has a good purity of 95%.
Q: How to get a free sample?
A: Contact our 24h/7d customer service online or directly send email to support@rscarebio.com, we will reply immediatly and provide 5g free samples for research and evaluation.
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Sales Office: Bestgrand Holdings Bldg, No. 6 Nanheng West Rd, Huizhou, PRC
R&D Center: Red Maple Hi-tech Industry Park, Nanjing, PRC
